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Context

Azelaic acid and pelargonic acid are produced by the oxidation of unsaturated fatty acids, a chemical reaction of interest for the synthesis of organic diacids used in the production of polymers and cross-linking agents. 

The use of ozone as an oxidant is widespread but requires expensive catalysts and specific solvents, such as pelargonic acid, to mitigate the risks of explosion due to the exothermic nature of
the reaction.

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Invention

This invention relates to the use of ozone for the simultaneous synthesis of azelaic acid and pelargonic acid. A synthesis process using ozone achieves a high equimolar yield of azelaic acid (obtained in crystalline form) and pelargonic acid (obtained in liquid form) without the need for organic solvents or catalysts, and with moderate energy consumption

Competitive advantages

  • Economic Efficiency and Process Simplicity: The method does not
    require a chemical catalyst and uses water as a solvent, eliminating
    the need for pre-introduced pelargonic acid as a solvent, which
    reduces raw material costs and simplifies the implementation
    process.
  • Simultaneous and Natural Production of Both Acids: The process
    directly generates an equimolar mixture of azelaic acid and pelargonic
    acid, optimizing overall yield while eliminating additional steps
    required to produce these compounds separately.
  • Improved Safety and Sustainability: Precise temperature control,
    homogeneous dispersion, and secure removal of residual ozone
    minimize risks associated with exothermic reactions and enhance
    environmental sustainability through better management of byproducts.
  • Flexibility and Product Quality: Crystallization and purification steps
    allow for the production of highly pure products, with customization
    possibilities according to industrial needs.

Key information

Applications

  • Pelargonic acid: Herbicides / Pharmaceutical Ingredient / Chemical Solvent
  • Azelaic acid: Dermocosmetics / Anti-acne

Markets

The markets for azelaic acid andpelargonic acid, estimated at USD194.3 million and USD 193.7 millionrespectively in 2024, are expected togrow at CAGRs exceeding 7% due totheir numerous applications inagriculture, pharmaceuticals, andchemistry.

Partnership

Seeking one or more industrial partners toexploit the patented invention (license ortransfer)

Intellectual Property

Patent family EP3280693 (Belgium, Switzerland, Germany, Spain, France, Italy, United Kingdom, Netherlands)

Development Stage : TRL8-9 

Qualified Complete System - Real system used in operational conditions

Development Scale

Contact us

Jean-Pierre GADONNA
Director of Valorization
+33 (0)3 44 06 38 10